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pentobarbital will decrease the level or effect of parecoxib by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Observe.pentobarbital will reduce the level or influence of duvelisib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration with a solid CYP3A inducer decreases duvelisib sp